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Anabolic steroids have some legitimate medical uses, including for treating hormonal issues in puberty, and to treat muscle loss caused by other diseases such as cancer and AIDS. But their abuse can cause side effects such as heart and liver problems, depression, and the eventual loss of the ability to conceive. "These substances are very dangerous because they can impair your judgment, your self-control, and possibly your ability to have a relationship with one's family," says Dr. David Mazer, a cardiologist at North Shore-LIJ Health System in Manhasset, New York. And since they affect the brain, they also have the potential to disrupt the production of endorphins, a natural chemical that helps relieve pain and increase appetite. "I think this is a particularly problematic problem given their tendency to increase aggression, depression, and aggression and also have a tendency to increase aggression for good reasons," Mazer says, calling the effects on the heart, liver, and kidney "very serious." One type of amphetamine pills, known as MPH (methylphenidate), has been linked to the deaths of thousands, and a study in the British Journal of Psychiatry found that it can lead to a worsening of brain function, as well as depression, psychosis, and increased blood pressure. But Dr. Daniela Herold, a psychologist at the University of Michigan School of Social Work in Ann Arbor, said the research needs to be taken with a grain of salt: "We could make the case that for some people amphetamines may be a useful medication for certain behavioral deficits, but this is a complex issue of potential side effects." But even if a patient does take an stimulant, it's important to remember there are other ways to help him or her stay focused and improve. "I would do anything that could help improve his concentration, and I would try to find ways to keep him from becoming fatigued," Herold says. "If there were something you could do that would not make him become depressed, but that would have an impact on his mood, I'd be going back to that again and again." This article is reproduced with permission from STAT. It was first published on June 15, 2014. Find the original story here. Similar articles: